This video details how to remove the OE Navigation system from a E53 X5 as well as the process and procedure for replacing a defective LCD screen. My screen had some dead pixels on it, that is why I replaced it.
Printable directions can be found here (I did not create these directions, I used them as a reference): http://www.xoutpost.com/article/E53%20Navigation%20Screen%20Replacement.pdf
The replacement LCD screen can be purchased here: http://www.eurotech-lcd.com/product.asp?s_id=262&l_id=89
This video uses a trim removal tool, which can be purchased here: http://amzn.to/GYcJgu
Note: THE USE OF THIS DIY IS FOR YOUR REFERENCE ONLY. I DISCLAIM ALL LIABILITY FOR DIRECT, INDIRECT, INCIDENTAL, OR CONSEQUENTIAL DAMAGES OR INJURIES THAT RESULT FROM ANY USE OF THE EXAMPLES, INSTRUCTIONS OR OTHER INFORMATION IN THIS DIY.